Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087340 | 0.90 | THRB (0.54) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL692374 | 0.90 | TSHR (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL6652309 | 0.89 | THRB (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL4849126 | 0.89 | THRB (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15081586 | 0.85 | THRB (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8962565 | 0.85 | TSHR (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2367366 | 0.84 | THRB (0.54) | THRBTSHRALDH1A1POLBAPEX1 | |
| Hexane SCHEMBL28941486 | 0.84 | TSHR (0.67) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL6509806 | 0.84 | THRB (0.54) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL23321704 | 0.83 | TSHR (0.61) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188224-A1 | METHOD FOR PRODUCING ONE-TERMINAL FUNCTIONAL ORGANOPOLYSILOXANE AND ONE-TERMINAL FUNCTIONAL ORGANOPOLYSILOXANE COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-06-12 | — | — | US | disclosed |
| EP-4506393-A1 | METHOD FOR PRODUCING ONE-END-FUNCTIONAL ORGANOPOLYSILOXANE AND ONE-END-FUNCTIONAL ORGANOPOLYSILOXANE COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023195358-A1 | METHOD FOR PRODUCING ONE-END-FUNCTIONAL ORGANOPOLYSILOXANE AND ONE-END-FUNCTIONAL ORGANOPOLYSILOXANE COMPOSITION | 信越化学工業株式会社 | 2023-10-12 | — | — | WO | disclosed |
| EP-2955207-B1 | SILICONE COMPOUND AND A USE THEREOF | SHINETSU CHEMICAL CO (JP) | 2018-02-14 | — | — | EP | disclosed |
| EP-2952515-B1 | SILICONE COMPOUND AND A USE THEREFORE | SHINETSU CHEMICAL CO (JP) | 2017-07-12 | — | — | EP | disclosed |
| EP-2921497-B1 | SILICONE COMPOUND AND A USE THEREOF | SHINETSU CHEMICAL CO (JP) | 2017-07-05 | — | — | EP | disclosed |
| EP-2873673-B1 | Silicone compound and a use thereof | SHINETSU CHEMICAL CO (JP) | 2017-06-28 | — | — | EP | disclosed |
| EP-2301986-B1 | One-terminal reactive organopolysiloxane having a polyalkyleneoxide group at the omega-terminal and a method for the preparation thereof | SHINETSU CHEMICAL CO (JP) | 2017-04-12 | — | — | EP | disclosed |
| EP-2955208-B1 | SILICONE COMPOUND AND A USE THEREOF | SHINETSU CHEMICAL CO (JP) | 2016-09-14 | — | — | EP | disclosed |
| US-9353135-B2 | Silicone compound and a use thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-05-31 | — | — | US | disclosed |
| EP-2873673-A2 | Silicone compound and a use thereof | Shin-Etsu Chemical Co., Ltd. (JP) | 2015-05-20 | — | — | EP | disclosed |
| US-20150133619-A1 | SILICONE COMPOUND AND A USE THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-05-14 | — | — | US | disclosed |
| EP-2128164-B1 | Silicone compound, a process for the preparation thereof and a process for the preparation of an ophthalmic device therefrom | SHINETSU CHEMICAL CO (JP) | 2013-12-18 | — | — | EP | disclosed |
| US-8404882-B2 | One-terminal reactive organopolysiloxane having a polyalkyleneoxide group at the omega-terminal and a method for the preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-03-26 | — | — | US | disclosed |
| US-8168735-B2 | Silicone compound, a process for the preparation thereof and a process for the preparation of an ophthalmic device therefrom | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20110077422-A1 | ONE-TERMINAL REACTIVE ORGANOPOLYSILOXANE HAVING A POLYALKYLENEOXIDE GROUP AT THE OMEGA-TERMINAL AND A METHOD FOR THE PREPARATION THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-03-31 | — | — | US | disclosed |
| EP-2301986-A1 | One-terminal reactive organopolysiloxane having a polyalkyleneoxide group at the omega-terminal and a method for the preparation thereof | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-03-30 | — | — | EP | disclosed |
| US-20090299022-A1 | SILICONE COMPOUND, A PROCESS FOR THE PREPARATION THEREOF AND A PROCESS FOR THE PREPARATION OF AN OPHTHALMIC DEVICE THEREFROM | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2009-12-03 | — | — | US | disclosed |
| EP-2128164-A1 | Silicone compound, a process for the preparation thereof and a process for the preparation of an ophthalmic device therefrom | Shin-Etsu Chemical Co., Ltd. (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-6310169-B1 | HYDROSILITION OF POLYETHERS AND POLYSILOXANES | CHISSO CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133619-A1 | SILICONE COMPOUND AND A USE THEREOF | STIM1, SMCHD1, SHC1 | THRB 2607/4885TSHR 3917/4885ALDH1A1 1799/4885 |
| US-20090299022-A1 | SILICONE COMPOUND, A PROCESS FOR THE PREPARATION THEREOF AND A PROCESS FOR THE PREPARATION OF AN OPHTHALMIC DEVICE THEREFROM | CARM1, SETD7, SETDB1 | THRB 3436/4885TSHR 2187/4885ALDH1A1 2927/4885 |
| US-20110077422-A1 | ONE-TERMINAL REACTIVE ORGANOPOLYSILOXANE HAVING A POLYALKYLENEOXIDE GROUP AT THE OMEGA-TERMINAL AND A METHOD FOR THE PREPARATION THEREOF | SCLY, IDUA, ALOX15B | THRB 173/4885TSHR 833/4885ALDH1A1 2202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.