Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167240 | 0.93 | LMNA (0.51) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL8087484 | 0.85 | LMNA (0.53) | LMNATSHRPMP22ADRA1ATK1 | |
| SCHEMBL8159691 | 0.84 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2TSHRPMP22TK1 | |
| SCHEMBL8091533 | 0.84 | TK1 (0.57) | LMNASMN1; SMN2TSHRPMP22ALOX12 | |
| SCHEMBL22647744 | 0.82 | LMNA (0.54) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL6752642 | 0.82 | LMNA (0.60) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL6752644 | 0.82 | LMNA (0.60) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL8087499 | 0.81 | LMNA (0.60) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL21345305 | 0.80 | LMNA (0.62) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL3437131 | 0.80 | LMNA (0.62) | LMNASMN1; SMN2MAPTESR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034087-A | VIRICIDE AGAINST HEPATITIS B | CHONG KUN DANG CORP. (KR) | 2000-03-07 | — | — | US | disclosed |