Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080110 | 0.85 | SMN1; SMN2 (0.60) | LMNAMAPTESR1SMN1; SMN2TSHR | |
| SCHEMBL8088562 | 0.85 | PYGM (0.48) | LMNAMAPTESR1SMN1; SMN2TSHR | |
| SCHEMBL8091552 | 0.85 | LMNA (0.51) | LMNATSHRPMP22ALDH1A1POLB | |
| SCHEMBL8088531 | 0.85 | TK1 (0.56) | LMNAMAPTESR1SMN1; SMN2TSHR | |
| SCHEMBL8087489 | 0.81 | LMNA (0.57) | LMNAMAPTESR1SMN1; SMN2TSHR | |
| SCHEMBL8104286 | 0.79 | LMNA (0.62) | LMNAMAPTESR1SMN1; SMN2TSHR | |
| SCHEMBL26296051 | 0.79 | LMNA (0.62) | LMNAMAPTESR1SMN1; SMN2TSHR | |
| SCHEMBL3437131 | 0.79 | LMNA (0.62) | LMNAMAPTESR1SMN1; SMN2TSHR | |
| SCHEMBL21345305 | 0.79 | LMNA (0.62) | LMNAMAPTESR1SMN1; SMN2TSHR | |
| SCHEMBL3437129 | 0.79 | LMNA (0.62) | LMNAMAPTESR1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3047045-B2 | — | — | 2000-05-29 | — | — | JP | claimed |
| US-6034087-A | VIRICIDE AGAINST HEPATITIS B | CHONG KUN DANG CORP. (KR) | 2000-03-07 | — | — | US | claimed |
| EP-0869953-A1 | NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | CHONG KUN DANG CORP (KR) | 1998-10-14 | — | — | EP | claimed |
| WO-1996012716-A1 | NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | CHONG KUN DANG CORP. (KR) | 1996-05-02 | — | — | WO | claimed |