Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | BCHE | P06276 | 4/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074144 | 0.86 | NQO1 (0.46) | NQO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15352430 | 0.81 | CYP1A2 (0.39) | NQO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15353313 | 0.81 | ACHE (0.35) | NQO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29919905 | 0.76 | NQO1 (0.67) | NQO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8393507 | 0.76 | NQO1 (0.67) | NQO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL315486 | 0.75 | CYP1A2 (0.45) | NQO1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8391116 | 0.74 | ALDH1A1 (0.59) | NQO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29862025 | 0.74 | ALDH1A1 (0.59) | NQO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2253565 | 0.72 | CYP1A2 (0.42) | NQO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21830291 | 0.71 | PDE4A (0.42) | KDM4EALDH1A1SMN1; SMN2MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937152-B2 | Non-selective somatostatin analogues | ITALFARMACO SPA (IT) | 2015-01-20 | — | — | US | claimed |
| EP-2225271-B1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2013-07-31 | — | — | EP | claimed |
| US-20100323964-A1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2010-12-23 | — | — | US | claimed |
| EP-2225271-A2 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO S.p.A. (IT) | 2010-09-08 | — | — | EP | claimed |
| WO-2009071460-A2 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2009-06-11 | — | — | WO | claimed |
| EP-2067786-A1 | Novel non selective analogs of somatostatin | ITALFARMACO S.p.A. (IT) | 2009-06-10 | — | — | EP | claimed |
| US-8937152-B2 | Non-selective somatostatin analogues | ITALFARMACO SPA (IT) | 2015-01-20 | — | — | US | disclosed |
| EP-2225271-B1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2013-07-31 | — | — | EP | disclosed |
| EP-1593674-B1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20100323964-A1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2010-12-23 | — | — | US | disclosed |
| EP-2225271-A2 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO S.p.A. (IT) | 2010-09-08 | — | — | EP | disclosed |
| US-7683215-B2 | Optically active bisoxazoline compounds, process for production of the same and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-23 | — | — | US | disclosed |
| US-7671213-B2 | Optically active bisoxazoline compounds, process for production of the same and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-02 | — | — | US | disclosed |
| US-20080076931-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF | ITAGAKI MAKOTO | 2008-03-27 | — | — | US | disclosed |
| US-20080076941-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF | ITAGAKI MAKOTO | 2008-03-27 | — | — | US | disclosed |
| CN-101125833-A | Optically active bisoxazoline compounds, process for production of the same and use thereof | SUMITOMO CHEMICAL CO (JP) | 2008-02-20 | — | — | CN | disclosed |
| US-7288674-B2 | Optically active bisoxazoline compounds, process for production of the same and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-30 | — | — | US | disclosed |
| US-20060149077-A1 | Optically active bisoxazoline compounds, process for production of the same and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
| CN-1771236-A | Optically active bisoxazoline compound, process for producing the same, and use thereof | SUMITOMO CHEMICAL CO (JP) | 2006-05-10 | — | — | CN | disclosed |
| EP-1593674-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2005-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060149077-A1 | Optically active bisoxazoline compounds, process for production of the same and use thereof | ACSL3, ADSL, SQLE | NQO1 434/4885KDM4E 3069/4885ALDH1A1 897/4885 |
| US-20080076941-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF | ACSL3, ADSL, SQLE | NQO1 434/4885KDM4E 3069/4885ALDH1A1 897/4885 |
| US-20100323964-A1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | SSTR4, SSTR1, SSTR3 | NQO1 4885/4885KDM4E 3796/4885ALDH1A1 4424/4885 |
| US-20080076931-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF | ACSL3, ADSL, SQLE | NQO1 434/4885KDM4E 3069/4885ALDH1A1 897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.