SCHEMBL29675199

SCHEMBL29675199

Cc1cc(Cc2ccccc2)ccc1Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.50
IDH1 O75874 1/20 0.48
LMNA P02545 1/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
BCL2 P10415 1/20 0.47
BCL2L1 Q07817 1/20 0.47
ALOX5 P09917 1/20 0.46
LTA4H P09960 1/20 0.45
LDHA P00338 1/20 0.43
LDHB P07195 1/20 0.43
CTRC Q99895 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4455072 1.00 CALM1 (0.50) CALM1IDH1LMNAESR1ESR2
SCHEMBL8087746 0.94 BCL2 (0.45) CALM1IDH1LMNABCL2BCL2L1
SCHEMBL8085589 0.91 LTA4H (0.44) CALM1IDH1LMNAESR1ESR2
SCHEMBL21305403 0.91 ALOX5 (0.43) CALM1IDH1LMNAESR1ESR2
SCHEMBL8993189 0.86 BCL2 (0.47) IDH1LMNABCL2BCL2L1ALOX5
SCHEMBL8101895 0.85 TAAR1 (0.43) ESR1ESR2LTA4H
SCHEMBL2140995 0.85 CALM1 (0.57) CALM1IDH1LMNABCL2BCL2L1
SCHEMBL8093981 0.84 TAAR1 (0.46) ESR1ESR2LTA4H
SCHEMBL146770 0.83 CALM1 (0.50) CALM1IDH1LMNAESR1ESR2
SCHEMBL3301748 0.83 CYP3A4 (0.53) CALM1LMNABCL2BCL2L1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114585678-B Polyolefin formulations resistant to thermal aging and flexibility 陶氏环球技术有限责任公司 2024-10-11 CN disclosed
EP-4061884-A1 HEAT AGING-RESISTANT AND FLEXIBLE POLYOLEFIN FORMULATION Dow Global Technologies LLC (US) 2022-09-28 EP disclosed
CN-114585678-A Thermal aging resistant and flexible polyolefin formulations 陶氏环球技术有限责任公司 2022-06-03 CN disclosed