Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.59 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.59 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | KDM5C | P41229 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL6135588 | 0.87 | GLRA1 (0.50) | GLRA1SLC6A9OR51E2TP53FFAR3 | |
| Glycine SCHEMBL9816937 | 0.83 | GLRA1 (0.46) | GLRA1SLC6A9OR51E2TP53FFAR3 | |
| Diethylamine SCHEMBL9699835 | 0.81 | — | — | |
| Propionic Acid SCHEMBL1014332 | 0.81 | FFAR3 (0.67) | OR51E2TP53FFAR3LDHASRR | |
| Malonic Acid SCHEMBL5874776 | 0.81 | LDHA (0.60) | OR51E2TP53FFAR3LDHASRR | |
| Malonic Acid SCHEMBL5874780 | 0.81 | LDHA (0.60) | OR51E2TP53FFAR3LDHASRR | |
| Propionic Acid SCHEMBL28428410 | 0.81 | FFAR3 (0.67) | OR51E2TP53FFAR3LDHASRR | |
| Glycine SCHEMBL2361724 | 0.81 | — | — | |
| Glycine SCHEMBL28449741 | 0.81 | — | — | |
| Diethylamine SCHEMBL4340639 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892447-A | Method for preparing high-purity alpha-dehydroamino acid compounds | ZHOU ZHIGUO | 2015-09-09 | — | — | CN | disclosed |
| US-6066316-A | AMPHOTERIC SURFACTANT AND OPTIONALLY A SEMI-POLAR SURFACTANT; NONIONIC SURFACTANT; AND WAX | SHISEIDO CO., LTD. (JP) | 2000-05-23 | — | — | US | disclosed |