Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14293862 | 0.91 | CA1 (0.49) | CA1CA2CA9CA14CA7 | |
| SCHEMBL14267920 | 0.87 | CA1 (0.56) | CA1CA2CA9CA14CA7 | |
| SCHEMBL9438607 | 0.84 | GID4 (0.58) | CA1CA2CA9CA14DRD1 | |
| SCHEMBL808897 | 0.82 | GID4 (0.55) | DRD1GID4 | |
| SCHEMBL29001208 | 0.82 | ALDH1A1 (0.48) | CA1CA2CA9CA14DRD1 | |
| SCHEMBL822036 | 0.78 | MAPT (0.56) | — | |
| SCHEMBL27861333 | 0.77 | LMNA (0.36) | CA1CA2CA9CA14 | |
| SCHEMBL6249142 | 0.77 | HTR2C (0.51) | CA1CA2CA9CA14DRD1 | |
| SCHEMBL3284717 | 0.77 | HTR2A (0.50) | CA1CA2CA9CA14DRD1 | |
| SCHEMBL1722733 | 0.76 | GAA (0.51) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168114-A1 | Oxone-Aceton Mediated Metal Free Preparation of Syn-Diols | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-16 | — | — | US | claimed |
| WO-2014207766-A1 | OXONE-ACETONE MEDIATED METAL FREE PREPARATION OF SYN-DIOLS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-31 | — | — | WO | claimed |
| US-10774060-B2 | Oxone-aceton mediated metal free preparation of syn-diols | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-09-15 | — | — | US | disclosed |
| US-10774060-B2 | Oxone-aceton mediated metal free preparation of syn-diols | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-09-15 | — | — | US | disclosed |
| US-20160168114-A1 | Oxone-Aceton Mediated Metal Free Preparation of Syn-Diols | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-16 | — | — | US | disclosed |
| US-20160168114-A1 | Oxone-Aceton Mediated Metal Free Preparation of Syn-Diols | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-16 | — | — | US | disclosed |
| US-20160168114-A1 | Oxone-Aceton Mediated Metal Free Preparation of Syn-Diols | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-16 | — | — | US | disclosed |
| WO-2014207766-A1 | OXONE-ACETONE MEDIATED METAL FREE PREPARATION OF SYN-DIOLS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-31 | — | — | WO | disclosed |
| EP-1955992-B1 | Process for the preparation of 1-aryl-3, 4-dihydro-1h-napthalene-2-one | TOKUYAMA CORP (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-7728154-B2 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | TOKUYAMA CORPORATION (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20080200697-A1 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | TOKUYAMA CORPORATION (JP) | 2008-08-21 | — | — | US | disclosed |
| EP-1955992-A2 | Process for the preparation of 1-aryl-3, 4-dihydro-1h-napthalene-2-one | TOKUYAMA CORPORATION (JP) | 2008-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200697-A1 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | SULT1E1, CYP2S1, SULT1A1 | CA1 1878/4885CA2 1289/4885CA9 2995/4885 |
| US-20160168114-A1 | Oxone-Aceton Mediated Metal Free Preparation of Syn-Diols | SQLE, OXER1, OXA1L | CA1 802/4885CA2 864/4885CA9 1278/4885 |
| US-10774060-B2 | Oxone-aceton mediated metal free preparation of syn-diols | SQLE, OXER1, OXA1L | CA1 802/4885CA2 864/4885CA9 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.