⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3589514 | 0.86 | BCL2L1 (0.42) | — | |
| SCHEMBL6711459 | 0.73 | BCL2L1 (0.42) | — | |
| SCHEMBL14931570 | 0.66 | CRBN (0.34) | — | |
| SCHEMBL1773996 | 0.63 | GABRA1 (0.32) | — | |
| SCHEMBL3283307 | 0.62 | BCL2L1 (0.56) | — | |
| SCHEMBL10802712 | 0.62 | BCL2L1 (0.50) | — | |
| SCHEMBL8092727 | 0.61 | — | — | |
| SCHEMBL1008746 | 0.60 | ADRB2 (0.32) | — | |
| SCHEMBL23674930 | 0.60 | CYP1A2 (0.45) | — | |
| SCHEMBL11560720 | 0.59 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043368-A | Method of making thieno-pyridine derivatives | POLI INDUSTRIA CHIMICA, S.P.A. (IT) | 2000-03-28 | — | — | US | disclosed |
| EP-0829482-A2 | Method of making thieno-pyridine derivatives | Poli Industria Chimica S.p.A. (IT) | 1998-03-18 | — | — | EP | disclosed |