SCHEMBL8089438

SCHEMBL8089438

C=CCc1cc(OC)ccc1S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.46
ALDH1A1 P00352 2/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
ALOX12 P18054 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HTR2C P28335 2/20 0.44
MAPT P10636 2/20 0.43
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PTPN1 P18031 3/20 0.41
APLNR P35414 1/20 0.40
POLB P06746 2/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21979437 0.83 ALDH1A1 (0.41) FFAR4ALDH1A1TP53CYP3A4ALOX15
SCHEMBL1804050 0.83 HSD17B10 (0.41) ALDH1A1MAPTL3MBTL1HSD17B10
SCHEMBL1607332 0.82 HSD17B10 (0.44) ALDH1A1MAPTLMNAL3MBTL1HSD17B10
SCHEMBL14991138 0.82 HSD17B10 (0.44) MAPTL3MBTL1HSD17B10
SCHEMBL1803005 0.81 HSD17B10 (0.42) SMN1; SMN2MAPTL3MBTL1HSD17B10
SCHEMBL1803007 0.81 HSD17B10 (0.42) ALDH1A1MAPTL3MBTL1HSD17B10
SCHEMBL1805381 0.80 HSD17B10 (0.40) L3MBTL1POLBHSD17B10
SCHEMBL2812505 0.80 POLB (0.41) ALDH1A1SMN1; SMN2MAPTLMNAL3MBTL1
SCHEMBL1804056 0.80 ADRA1A (0.44) MAPTHSD17B10
SCHEMBL9807158 0.79 CASP1 (0.35) SMN1; SMN2MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0766757-B1 ACRYLIC FIBER WITH HIGH OPTICAL BRIGHTNESS MONSANTO CO (US) 2000-12-06 EP disclosed
US-6066687-A A FIBER FORMED FROM AN ACRYLONITRILE POLYMER AND COMPRISING A DELUSTRANT AND AN OPTICAL BRIGHTENER, CHARACTERIZED BY A BRIGHTNESS VALUE OF ATLEAST ABOUT 79 SOLUTIA INC. (US) 2000-05-23 US disclosed
WO-1999005986-A1 IMPROVED DENTAL FLOSS WHITEHILL ORAL TECHNOLOGIES, INC. (US) 1999-02-11 WO disclosed
US-5232647-A Process of making bicomponent acrylic fibers having reversible crimp AMERICAN CYANAMID COMPANY (US) 1993-08-03 US disclosed
US-5130195-A Hydrophilic sulfonated polyacrylonitrile AMERICAN CYANAMID COMPANY (US) 1992-07-14 US disclosed
EP-0490052-A2 Reversible crimp bicomponent acrylic fibers CYTEC TECHNOLOGY CORP. (US) 1992-06-17 EP disclosed
US-4524105-A CONTAINING BLOCK OF POLYVINYL ALCOHOL; DYEABILITY AMERICAN CYANAMID COMPANY (US) 1985-06-18 US disclosed
US-4418176-A Self-crimping acrylic fiber from a melt of two non-compatible polymers AMERICAN CYANAMID COMPANY (US) 1983-11-29 US disclosed
US-4301112-A Process for biaxially oriented acrylonitrile polymer barrier film AMERICAN CYANAMID COMPANY (US) 1981-11-17 US disclosed
US-4301104-A DISPERSING TWO POLYMERS WITH DIFFERENT PROPERTIES AMERICAN CYANAMID COMPANY (US) 1981-11-17 US disclosed
US-4301107-A TWO-STAGE STRETCHING AMERICAN CYANAMID COMPANY (US) 1981-11-17 US disclosed
US-4296175-A FOR TEXTILES AMERICAN CYANAMID COMPANY (US) 1981-10-20 US disclosed
US-4255532-A A GRAFT POLYMER COMPRISING ACRYLONITRILE, POLYVINYL ALCOHOL, AND AN ACRYLIC ESTER; TEXTILE FIBERS; DYEABILITY AMERICAN CYANAMID COMPANY (US) 1981-03-10 US disclosed
EP-0014803-A1 Process for preparing acrylonitrile polymer fiber of hollow or open structure AMERICAN CYANAMID COMPANY (US) 1980-09-03 EP disclosed
US-4205039-A CONTAINING HYDROPHOBIC MONOMERS AND A HYDROPHILIC MOIETY TO FORM A SINGLE PHASE MELT USING A MINIMUM AMOUNT OF WATER AMERICAN CYANAMID COMPANY (US) 1980-05-27 US disclosed
US-4163770-A Melt-spinning acrylonitrile polymer fibers AMERICAN CYANAMID COMPANY (US) 1979-08-07 US disclosed