SCHEMBL8089482

SCHEMBL8089482

CC(C)N1CCCN(C(C)C)C1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PER2 O15055 3/20 0.37
CRY2 Q49AN0 1/20 0.37
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.34
PIK3CD O00329 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
LMNA P02545 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL596921 0.88 PER2 (0.38) PER2CRY2ALDH1A1MAPTPIK3CD
SCHEMBL1106515 0.85 BRD4 (0.39) PER2CRY2ALDH1A1MAPTPIK3CD
SCHEMBL24687997 0.80 BRD4 (0.39) PER2CRY2ALDH1A1MAPTPIK3CD
SCHEMBL13918278 0.80 PER2 (0.43) PER2CRY2PIK3CDLMNACA12
SCHEMBL19443027 0.80 PER2 (0.36) PER2CRY2PIK3CD
SCHEMBL19872806 0.79 PER2 (0.42) PER2CRY2PIK3CDLMNACA12
SCHEMBL23714591 0.79 NPY5R (0.38) PER2CRY2
SCHEMBL24848139 0.77 PER2 (0.33) PER2CRY2ALDH1A1MAPT
SCHEMBL25703614 0.77 PER2 (0.33) PER2CRY2ALDH1A1MAPT
SCHEMBL26141151 0.77 MAPK1 (0.38) PER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230387464-A1 Nonaqueous Electrolytic Solution and Nonaqueous Electrolytic Solution Battery MU IONIC SOLUTIONS CORPORATION (JP) 2023-11-30 US disclosed
US-20230387464-A1 Nonaqueous Electrolytic Solution and Nonaqueous Electrolytic Solution Battery MU IONIC SOLUTIONS CORPORATION (JP) 2023-11-30 US disclosed
US-10179793-B2 ACC inhibitors and uses thereof GILEAD APOLLO, LLC (US) 2019-01-15 US disclosed
US-20170145028-A1 ACC INHIBITORS AND USES THEREOF GILEAD APOLLO, LLC (US) 2017-05-25 US disclosed
US-20170145028-A1 ACC INHIBITORS AND USES THEREOF GILEAD APOLLO, LLC (US) 2017-05-25 US disclosed
WO-2017075056-A1 ACC INHIBITORS AND USES THEREOF GILEAD APOLLO, LLC (US) 2017-05-04 WO disclosed
US-8933012-B2 Glycopeptide antibiotic derivative SHIONOGI & CO., LTD. (JP) 2015-01-13 US disclosed
US-8778874-B2 Glycopeptide antibiotic monomer derivatives NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-07-15 US disclosed
US-20090286717-A1 Glycopeptide Antibiotic Derivative SHIONOGI & CO., LTD. (JP) 2009-11-19 US disclosed
US-20080097078-A1 Antibacterial activity against vancomycin-resistant bacteria SHIONOGI & CO., LTD. (JP) 2008-04-24 US disclosed
EP-1054297-A1 PHOTORESIST STRIPPER AND METHOD OF STRIPPING Clariant International Ltd. (CH) 2000-11-22 EP disclosed
US-4918186-A Process for producing cyclic ureas MITSUI TOATSU CHEMICALS, INC. (JP) 1990-04-17 US disclosed
EP-0248220-A2 Process for producing cyclic ureas MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170145028-A1 ACC INHIBITORS AND USES THEREOF ACACA, ACACB, ACAT2 PER2 4070/4885CRY2 4373/4885ALDH1A1 104/4885
US-10179793-B2 ACC inhibitors and uses thereof ACACA, ACACB, ACAT2 PER2 4070/4885CRY2 4373/4885ALDH1A1 104/4885
US-20090286717-A1 Glycopeptide Antibiotic Derivative NR2C2, NR0B2, NR3C2 PER2 741/4885CRY2 369/4885ALDH1A1 3967/4885
US-20080097078-A1 Antibacterial activity against vancomycin-resistant bacteria CSGALNACT1, MON2, NR2C2 PER2 916/4885CRY2 1250/4885ALDH1A1 2289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.