Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103262 | 0.85 | MAPT (0.62) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8089677 | 0.82 | MAPT (0.64) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8098719 | 0.78 | MAPT (0.59) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL4786129 | 0.76 | MAPT (0.55) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL8089825 | 0.76 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8082058 | 0.75 | MAPT (0.59) | MAPTKMT2AMEN1SMN1; SMN2NOTUM | |
| SCHEMBL8097250 | 0.74 | MAPT (1.00) | MAPTKMT2AMEN1ALDH1A1NOTUM | |
| SCHEMBL8103751 | 0.72 | MAPT (0.55) | MAPTNOTUM | |
| SCHEMBL8099175 | 0.70 | MAPT (0.58) | MAPTALDH1A1NOTUM | |
| SCHEMBL8106122 | 0.69 | MAPT (0.66) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |