Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097072 | 0.88 | METAP2 (0.35) | TYRMETAP2ALOX5RIPK1 | |
| SCHEMBL21399635 | 0.83 | TYR (0.47) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL18364622 | 0.82 | TYR (0.50) | TYRMETAP2HTTMEN1TP53 | |
| SCHEMBL28021402 | 0.80 | TYR (0.44) | TYRMETAP2HTTMEN1TP53 | |
| SCHEMBL11774668 | 0.79 | TYR (0.46) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL13692432 | 0.79 | TAAR1 (0.45) | MEN1MAPTALOX15KMT2ATDP1 | |
| SCHEMBL8097082 | 0.79 | RIPK1 (0.38) | METAP2RIPK1 | |
| SCHEMBL25944918 | 0.78 | TYR (0.47) | TYRMETAP2HTTMEN1TP53 | |
| SCHEMBL26240937 | 0.78 | TYR (0.47) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL8090805 | 0.76 | TYR (0.40) | TYRCYP3A4ALOX5LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053990-A2 | A method of producing an aromatic ketone and an aromatic ketone composition containing it | TORAY INDUSTRIES, INC. (JP) | 2000-11-22 | — | — | EP | disclosed |