Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 13/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22967685 | 0.83 | RIPK1 (0.35) | RIPK1P2RX7METAP2 | |
| SCHEMBL8097072 | 0.82 | METAP2 (0.35) | RIPK1P2RX7METAP2 | |
| SCHEMBL18566713 | 0.81 | P2RX7 (0.33) | RIPK1P2RX7HDAC4GPR84 | |
| SCHEMBL11967063 | 0.81 | RIPK1 (0.38) | RIPK1METAP2 | |
| SCHEMBL1547626 | 0.80 | RIPK1 (0.47) | RIPK1P2RX7CES2CES1 | |
| SCHEMBL4621794 | 0.79 | LOXL2 (0.38) | RIPK1P2RX7HDAC4GPR84 | |
| SCHEMBL4621597 | 0.79 | PDCD1 (0.39) | RIPK1P2RX7HDAC4METAP2CES2 | |
| SCHEMBL22527189 | 0.79 | P2RX7 (0.42) | RIPK1P2RX7 | |
| SCHEMBL5156289 | 0.79 | P2RX7 (0.32) | RIPK1P2RX7HDAC4GPR84 | |
| SCHEMBL9177096 | 0.79 | HDAC4 (0.33) | RIPK1P2RX7HDAC4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212693-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2023-11-02 | — | — | WO | disclosed |
| EP-2794611-B1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2017-10-11 | — | — | EP | disclosed |
| EP-1053990-A2 | A method of producing an aromatic ketone and an aromatic ketone composition containing it | TORAY INDUSTRIES, INC. (JP) | 2000-11-22 | — | — | EP | disclosed |