Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.33 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL471957 | 0.72 | PTGER4 (0.31) | PTGER4PTGER3PTGER2 | |
| SCHEMBL27165392 | 0.72 | KMT2A (0.34) | PTGER4PTGER3PTGER2GSTK1ENPEP | |
| SCHEMBL30773222 | 0.71 | ALDH1A1 (0.49) | PTGER4PTGER3PTGER2GSTK1ENPEP | |
| SCHEMBL949638 | 0.71 | ALDH1A1 (0.35) | ALDH1A1PKM | |
| SCHEMBL4310967 | 0.70 | GSTK1 (0.37) | PTGER4PTGER3PTGER2GSTK1ENPEP | |
| SCHEMBL846234 | 0.70 | ALDH1A1 (0.47) | PTGER4PTGER3PTGER2GSTK1HDAC3 | |
| SCHEMBL17821007 | 0.70 | ALDH1A1 (0.47) | PTGER4PTGER3PTGER2GSTK1HDAC3 | |
| Ethylene Glycol SCHEMBL31079756 | 0.70 | ALDH1A1 (0.35) | ALDH1A1PKM | |
| SCHEMBL826505 | 0.69 | LMNA (0.39) | PTGER4PTGER3PTGER2GSTK1MEN1 | |
| SCHEMBL825651 | 0.69 | LMNA (0.39) | PTGER4PTGER3PTGER2GSTK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856055-A1 | STREPTAVIDIN MUTANTS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1998-08-05 | — | — | EP | claimed |
| WO-1997011183-A1 | STREPTAVIDIN MUTANTS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1997-03-27 | — | — | WO | claimed |
| US-6022951-A | MODIFIED ANTIBIOTIC PEPTIDE FOR INCREASED OR DECREASED SENSITIVITY TO BIOTIN, AND METHODS FOR UTILIZING THESE PROTEINS IN DETECTION, ISOLATION AND PURIFICATION TECHNIQUES | U.S. DEPARTMENT OF ENERGY | 2000-02-08 | — | — | US | disclosed |
| EP-0856055-A1 | STREPTAVIDIN MUTANTS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997011183-A1 | STREPTAVIDIN MUTANTS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1997-03-27 | — | — | WO | disclosed |