Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | ROS1 | P08922 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090035 | 0.80 | SMN1; SMN2 (0.54) | EGFRSMN1; SMN2CYP3A4MAOBCYP1A2 | |
| SCHEMBL8084817 | 0.78 | HTR2C (0.43) | SMN1; SMN2CYP3A4LMNACYP1A2CYP2C19 | |
| SCHEMBL8089979 | 0.74 | CYP1A2 (0.51) | SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL8908139 | 0.73 | HTR1A (0.47) | KCNH2CYP3A4CYP1A2CYP2C19HIF1A | |
| SCHEMBL2333890 | 0.73 | HTR1A (0.47) | KCNH2CYP3A4CYP1A2CYP2C19HIF1A | |
| SCHEMBL12796611 | 0.71 | LOXL2 (0.53) | SMN1; SMN2CYP3A4CYP1A2CYP2C19HIF1A | |
| SCHEMBL1387262 | 0.71 | ERBB2 (0.71) | CHEK2EGFRERBB2ROS1FLT3 | |
| SCHEMBL31197401 | 0.71 | ERBB2 (0.71) | CHEK2EGFRERBB2ROS1FLT3 | |
| Hydrochloric Acid SCHEMBL8808393 | 0.70 | ERBB2 (0.69) | CHEK2EGFRERBB2ROS1FLT3 | |
| SCHEMBL8811488 | 0.70 | LMNA (0.71) | CHEK2EGFRERBB2ROS1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |