Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090141 | 0.94 | CHRM5 (0.36) | CHRM5CHRM3MMP8CYP3A4CYP2C19 | |
| SCHEMBL8095467 | 0.84 | CYP3A4 (0.38) | MMP8CYP3A4CYP2C19TACR1TACR3 | |
| SCHEMBL8090113 | 0.84 | CYP2C19 (0.38) | CHRM5CHRM3MMP8CYP3A4CYP2C19 | |
| SCHEMBL8095269 | 0.83 | MMP1 (0.38) | MMP8CYP3A4CYP2C19EPHX1 | |
| Hydrochloric Acid SCHEMBL7432966 | 0.83 | F2 (0.37) | CHRM5CHRM3MMP8CYP3A4CYP2C19 | |
| SCHEMBL8090189 | 0.82 | MMP8 (0.37) | MMP8CYP3A4CYP2C19TACR1TACR3 | |
| SCHEMBL8098091 | 0.79 | MMP8 (0.43) | MMP8CYP2C19ALDH1A1NPC1EPHX2 | |
| SCHEMBL8095221 | 0.79 | MMP8 (0.41) | MMP8CYP2C19EPHX2CNR1 | |
| SCHEMBL8090112 | 0.77 | CYP2C19 (0.39) | MMP8CYP3A4CYP2C19TACR1TACR3 | |
| SCHEMBL8095466 | 0.77 | CYP2C19 (0.39) | MMP8CYP3A4CYP2C19TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |