Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089008 | 0.83 | IDO1 (0.33) | — | |
| SCHEMBL7819041 | 0.80 | CYP1A2 (0.44) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL8090023 | 0.71 | ALDH1A1 (0.33) | ALDH1A1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL23948606 | 0.64 | NOTUM (0.46) | ALDH1A1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL30388360 | 0.64 | TSHR (0.39) | ALDH1A1HSD17B10ALOX15NOTUMDRD2 | |
| SCHEMBL29854091 | 0.62 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL8553895 | 0.62 | CYP3A4 (0.42) | ALDH1A1HSD17B10MAPTNOTUMDRD2 | |
| SCHEMBL10729227 | 0.61 | TSHR (0.36) | ALDH1A1HSD17B10KMT2ADRD2DRD3 | |
| SCHEMBL11595049 | 0.60 | IDH1 (0.40) | ALDH1A1HSD17B10DRD2DRD3TSHR | |
| SCHEMBL6200917 | 0.59 | ALDH1A1 (0.40) | ALDH1A1HSD17B10MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022976-A | Process for the production of 5-hydroxyoxazolidinones | ZENECA LIMITED | 2000-02-08 | — | — | US | disclosed |
| EP-0880510-A1 | PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES | ZENECA LIMITED (GB) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028138-A1 | PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES | ZENECA LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |