SCHEMBL8089008

SCHEMBL8089008

O=C1C(O)OCN1c1cc(Cl)c(F)c(Cl)c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7819041 0.84 CYP1A2 (0.44) IDO1TDO2
SCHEMBL8090197 0.83 ALDH1A1 (0.35)
SCHEMBL6508357 0.78 IDO1 (0.31) IDO1TDO2
SCHEMBL5827283 0.68 MEN1 (0.46)
SCHEMBL8666490 0.64 KMT2A (0.35)
SCHEMBL8666484 0.64 GRM2 (0.41)
SCHEMBL8098980 0.61
SCHEMBL8090534 0.60 KAT2B (0.48)
SCHEMBL11556294 0.59 KMT2A (0.34) IDO1TDO2
SCHEMBL11666213 0.59 MGLL (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6022976-A Process for the production of 5-hydroxyoxazolidinones ZENECA LIMITED 2000-02-08 US disclosed
EP-0880510-A1 PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES ZENECA LIMITED (GB) 1998-12-02 EP disclosed
WO-1997028138-A1 PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES ZENECA LIMITED (GB) 1997-08-07 WO disclosed