Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090199 | 0.93 | TAS1R3 (0.34) | TAS1R3TAS1R1FNTAFNTBALDH1A1 | |
| SCHEMBL8091548 | 0.89 | HPGDS (0.31) | TAS1R3TAS1R1FNTAFNTB | |
| SCHEMBL8091556 | 0.88 | CTSB (0.33) | TAS1R3TAS1R1ALDH1A1LNPEPHPGD | |
| SCHEMBL8095195 | 0.88 | F10 (0.33) | TAS1R3TAS1R1FNTAFNTBALDH1A1 | |
| SCHEMBL8091543 | 0.82 | HPGDS (0.32) | TAS1R3TAS1R1FNTAFNTBALDH1A1 | |
| SCHEMBL8091555 | 0.81 | CTSB (0.33) | TAS1R3TAS1R1ALDH1A1LNPEPHPGD | |
| SCHEMBL8098190 | 0.79 | CTSB (0.32) | TAS1R3TAS1R1LNPEPERAP2ERAP1 | |
| SCHEMBL8091681 | 0.79 | L3MBTL1 (0.32) | TAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL8083597 | 0.78 | L3MBTL1 (0.31) | TAS1R3TAS1R1 | |
| SCHEMBL8083411 | 0.77 | F10 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |