Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13126722 | 0.83 | SLC22A2 (0.32) | SLC22A2SLC47A1 | |
| SCHEMBL16448448 | 0.83 | SLC22A2 (0.32) | SLC22A2SLC47A1 | |
| SCHEMBL8089730 | 0.73 | HSD11B1 (0.32) | — | |
| SCHEMBL12765771 | 0.72 | CYP2C9 (0.38) | — | |
| SCHEMBL28233988 | 0.72 | CYP2C9 (0.43) | — | |
| SCHEMBL12765492 | 0.72 | — | — | |
| SCHEMBL679325 | 0.71 | CYP2C9 (0.41) | — | |
| SCHEMBL12765505 | 0.68 | THRB (0.32) | — | |
| SCHEMBL12765493 | 0.68 | — | — | |
| SCHEMBL12765503 | 0.68 | CYP2C9 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661271-B1 | AZEPINE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS SIGMA-RECEPTOR LIGANDS | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5658923-A | USED IN TREATING DISEASES RELATED TO SIGMA-RECEPTOR, SUCH AS SCHIZOPHRENIA | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0661271-A1 | AZEPINE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-07-05 | — | — | EP | disclosed |