Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090313 | 0.85 | MAPT (0.44) | MAPTNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL8099041 | 0.78 | MCHR1 (0.38) | MAPTNPBWR1MCHR1DPP4FGFR2 | |
| SCHEMBL8105974 | 0.77 | MEN1 (0.49) | MAPTNPC1TP53TSHRNFKB1 | |
| SCHEMBL8090310 | 0.76 | POLB (0.51) | MAPTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL8098928 | 0.76 | MAPT (0.44) | MAPTDPP4NOX4 | |
| SCHEMBL8099334 | 0.76 | MGLL (0.49) | MAPTTP53 | |
| SCHEMBL8099176 | 0.75 | DPP4 (0.38) | NPBWR1MCHR1DPP4FGFR2FGFR3 | |
| SCHEMBL8099139 | 0.75 | MAPT (0.36) | MAPTLMNATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8787841 | 0.73 | CYP11B2 (0.40) | MAPT | |
| SCHEMBL8787824 | 0.71 | MAPT (0.45) | MAPTLMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |