Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.65 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanine SCHEMBL72148 | 0.92 | PNP (0.77) | PNPGDAACHEALDH1A1HPGD | |
| Guanine SCHEMBL28135092 | 0.91 | PNP (0.74) | PNPGDAACHEALDH1A1HPGD | |
| Guanine SCHEMBL629581 | 0.90 | PNP (0.72) | PNPGDAACHEALDH1A1HPGD | |
| Guanine SCHEMBL28018185 | 0.86 | PNP (0.67) | PNPGDAACHEALDH1A1HPGD | |
| Guanine SCHEMBL28068968 | 0.84 | PNP (0.63) | PNPGDAACHEALDH1A1HPGD | |
| Guanine SCHEMBL28067184 | 0.83 | PNP (0.79) | PNPGDAALDH1A1HPGDUSP2 | |
| Guanine SCHEMBL1264884 | 0.81 | PNP (1.00) | PNPGDAALDH1A1HPGDMAPT | |
| Guanine SCHEMBL986801 | 0.81 | PNP (1.00) | PNPGDAALDH1A1HPGDMAPT | |
| Guanine SCHEMBL5260 | 0.81 | PNP (1.00) | PNPGDAALDH1A1HPGDMAPT | |
| Guanine SCHEMBL22533907 | 0.79 | PNP (0.96) | PNPGDAALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053022-A2 | SENSITIZING CELLS TO COMPOUNDS USING LIPID-MEDIATED GENE AND COMPOUND DELIVERY | Inex Pharmaceuticals Corp. (CA) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999039740-A9 | SENSITIZING CELLS TO COMPOUNDS USING LIPID-MEDIATED GENE AND COMPOUND DELIVERY | INEX PHARMACEUTICALS CORP (CA) | 1999-11-25 | — | — | WO | disclosed |
| WO-1999039740-A2 | SENSITIZING CELLS TO COMPOUNDS USING LIPID-MEDIATED GENE AND COMPOUND DELIVERY | INEX PHARMACEUTICALS CORPORATION (CA) | 1999-08-12 | — | — | WO | disclosed |