Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 4/20 | 0.63 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanine SCHEMBL72148 | 0.91 | PNP (0.77) | PNPGDAACHEGRIA1GRIA2 | |
| Guanine SCHEMBL28135092 | 0.90 | PNP (0.74) | PNPGDAACHEGRIA1GRIA2 | |
| Guanine SCHEMBL641789 | 0.90 | PNP (0.79) | PNPGDAGRIA1GRIA2GRIA3 | |
| Guanine SCHEMBL629581 | 0.89 | PNP (0.72) | PNPGDAACHEGRIA1GRIA2 | |
| Xanthine SCHEMBL27853109 | 0.85 | ACHE (0.77) | PNPGDAACHEGRIA1GRIA2 | |
| Guanine SCHEMBL28018185 | 0.85 | PNP (0.67) | PNPGDAACHEGRIA1GRIA2 | |
| Guanine SCHEMBL8090344 | 0.84 | PNP (0.65) | PNPGDAACHEGRIA1GRIA2 | |
| Guanine SCHEMBL28064900 | 0.84 | PNP (0.58) | PNPGDAACHEGRIA1GRIA2 | |
| Guanine SCHEMBL27782399 | 0.83 | PNP (0.63) | PNPGDAGRIA1GRIA2GRIA3 | |
| Guanine SCHEMBL27753678 | 0.82 | PNP (0.79) | PNPGDAGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764924-A | Modified anti-epidermal growth factor receptor antibodies and methods of use thereof | 哈洛齐梅公司 | 2016-07-13 | — | — | CN | disclosed |