Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174060 | 0.82 | — | — | |
| SCHEMBL8085262 | 0.81 | — | — | |
| SCHEMBL8088478 | 0.75 | — | — | |
| SCHEMBL8085398 | 0.67 | — | — | |
| SCHEMBL8088681 | 0.67 | — | — | |
| SCHEMBL8084438 | 0.67 | ABCC9 (0.44) | KDM4E | |
| SCHEMBL9443482 | 0.65 | ALDH1A1 (0.31) | — | |
| SCHEMBL8090541 | 0.65 | AKR1B1 (0.32) | — | |
| SCHEMBL8085421 | 0.65 | HTR1A (0.32) | — | |
| SCHEMBL10696875 | 0.65 | ABCC9 (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |