Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091901 | 0.87 | LMNA (0.40) | SERPINE1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL8091742 | 0.80 | SERPINE1 (0.52) | SERPINE1LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL8091902 | 0.80 | SERPINE1 (0.49) | SERPINE1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL8091853 | 0.77 | SERPINE1 (0.52) | SERPINE1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL8090611 | 0.77 | SERPINE1 (0.55) | SERPINE1LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL8090673 | 0.77 | SERPINE1 (0.55) | SERPINE1LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL5563828 | 0.76 | HTT (0.40) | LMNAALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL8083705 | 0.76 | SERPINE1 (0.49) | SERPINE1LMNAMAPTHTTKMT2A | |
| SCHEMBL8123179 | 0.76 | SERPINE1 (0.54) | SERPINE1LMNAALDH1A1MAPTCYP1A2 | |
| SCHEMBL5562651 | 0.74 | MAPT (0.48) | LMNAALDH1A1MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |