Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | RHOC | P08134 | 1/20 | 0.34 |
| ▸ | RHOA | P61586 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083940 | 0.87 | RHOC (0.36) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL8090682 | 0.83 | MAPT (0.42) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL8091881 | 0.83 | MAPT (0.43) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL8171363 | 0.83 | SERPINE1 (0.40) | MAPTLMNAKMT2AMEN1SERPINE1 | |
| SCHEMBL8083684 | 0.82 | SERPINE1 (0.40) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL8091948 | 0.80 | SERPINE1 (0.41) | MAPTLMNAKMT2AMEN1SERPINE1 | |
| SCHEMBL8091935 | 0.80 | SERPINE1 (0.47) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL8092259 | 0.79 | USP10 (0.44) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL7913903 | 0.78 | POLB (0.49) | MAPTLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8083705 | 0.76 | SERPINE1 (0.49) | MAPTLMNAKMT2AMEN1SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |