Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP10 | Q14694 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083684 | 0.88 | SERPINE1 (0.40) | ALDH1A1MAPTRAB9ANPC1PKM | |
| SCHEMBL8090776 | 0.87 | PTGER4 (0.38) | ALDH1A1MAPTPTGER4LMNAKDM4E | |
| SCHEMBL8092253 | 0.85 | USP10 (0.48) | USP10ALDH1A1MAPTRAB9APTGER4 | |
| SCHEMBL8091935 | 0.85 | SERPINE1 (0.47) | ALDH1A1MAPTRAB9ANPC1PKM | |
| SCHEMBL8098482 | 0.79 | MAPT (0.39) | ALDH1A1MAPTRAB9ANPC1LMNA | |
| SCHEMBL8090682 | 0.79 | MAPT (0.42) | ALDH1A1MAPTRAB9ANPC1LMNA | |
| SCHEMBL8091948 | 0.79 | SERPINE1 (0.41) | ALDH1A1MAPTPKMLMNAPOLB | |
| SCHEMBL8171363 | 0.78 | SERPINE1 (0.40) | ALDH1A1MAPTPKMLMNAPOLB | |
| SCHEMBL8091918 | 0.77 | SERPINE1 (0.50) | MAPTLMNAKMT2ASERPINE1MEN1 | |
| SCHEMBL8091902 | 0.75 | SERPINE1 (0.49) | ALDH1A1MAPTRAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |