Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098272 | 0.87 | UBE2M (0.34) | PPARGPPARD | |
| SCHEMBL8090682 | 0.87 | MAPT (0.42) | MEN1MAPTKMT2A | |
| SCHEMBL8098738 | 0.82 | CYP1A2 (0.33) | — | |
| SCHEMBL8083940 | 0.81 | RHOC (0.36) | PPARGPPARDS1PR3MEN1MAPT | |
| SCHEMBL8083649 | 0.81 | S1PR1 (0.37) | PPARGPPARDS1PR1S1PR4S1PR3 | |
| SCHEMBL8098790 | 0.80 | NPSR1 (0.36) | MAPT | |
| SCHEMBL8090776 | 0.77 | PTGER4 (0.38) | PPARGMEN1MAPTKMT2A | |
| SCHEMBL8181084 | 0.76 | CFTR (0.51) | S1PR1S1PR3 | |
| SCHEMBL8083716 | 0.75 | AKR1C3 (0.37) | PPARGMEN1MAPTKMT2A | |
| SCHEMBL8083684 | 0.75 | SERPINE1 (0.40) | MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |