Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936342 | 0.80 | ESR1 (0.53) | LMNABACE1MEN1KMT2AMAPT | |
| SCHEMBL21694726 | 0.79 | ALDH1A1 (0.58) | LMNAGSTA1MAPTMMP2PRKCB | |
| SCHEMBL92724 | 0.77 | AKR1C3 (0.52) | LIG1LMNAGSTA1MEN1KMT2A | |
| SCHEMBL18529872 | 0.76 | GSTA1 (0.50) | LIG1LMNAGSTA1MAPTRAB9A | |
| SCHEMBL27271193 | 0.75 | ALDH1A1 (0.47) | BACE1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL623796 | 0.73 | ALDH1A1 (0.61) | LMNAGSTA1MAPTALDH1A1HPGD | |
| SCHEMBL28312144 | 0.72 | BACE1 (0.51) | LMNABACE1MEN1KMT2AMAPT | |
| SCHEMBL9065832 | 0.72 | KMT2A (0.56) | LIG1LMNAMEN1KMT2AMAPT | |
| SCHEMBL13589361 | 0.72 | GSTA1 (0.83) | LIG1LMNAGSTA1MEN1KMT2A | |
| SCHEMBL5013557 | 0.71 | ABL1 (0.52) | LIG1LMNAGSTA1BACE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637613-B1 | RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2000-10-25 | — | — | EP | disclosed |
| US-5543474-A | BLEND OF A AROMATIC POLYAMIDEIMIDE COPOLYMER AND A POLYESTER | MITSUBISHI GAS COMPANY, INC. (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0637613-A1 | RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1995-02-08 | — | — | EP | disclosed |