Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346526 | 1.00 | CYP3A4 (0.46) | CYP3A4TSHRPDK2IDO1STS | |
| SCHEMBL10346361 | 1.00 | CYP3A4 (0.46) | CYP3A4TSHRPDK2IDO1STS | |
| SCHEMBL31195429 | 1.00 | CYP3A4 (0.46) | CYP3A4TSHRPDK2IDO1STS | |
| SCHEMBL126258 | 0.98 | CYP3A4 (0.47) | CYP3A4TSHRPDK2IDO1STS | |
| Cyclohexanone SCHEMBL10801298 | 0.89 | PDK2 (0.44) | CYP3A4TSHRPDK2STSALDH1A1 | |
| Cycloheptanone SCHEMBL10800897 | 0.89 | PDK2 (0.44) | CYP3A4TSHRPDK2STSALDH1A1 | |
| SCHEMBL4583083 | 0.87 | RAPGEF4 (0.41) | CYP3A4TSHRPDK2STSALDH1A1 | |
| SCHEMBL3427795 | 0.86 | KDM4E (0.49) | CYP3A4TSHRALDH1A1MAPTMAPK1 | |
| SCHEMBL3768702 | 0.84 | KDM4E (0.46) | CYP3A4TSHRALDH1A1MAPTMAPK1 | |
| SCHEMBL10346907 | 0.82 | RAPGEF4 (0.45) | CYP3A4TSHRALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104412-A | With N-cycloalkyl-3-aminophenols as coupling compounds; colorfast brown, heat, light, chemical resistance | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1992-04-14 | — | — | US | claimed |
| JP-3240761-A | — | — | None | — | — | JP | disclosed |
| JP-4001160-A | — | — | None | — | — | JP | disclosed |
| JP-5078610-A | — | — | None | — | — | JP | disclosed |
| JP-3240758-A | — | — | None | — | — | JP | disclosed |
| JP-62000528-A | — | — | None | — | — | JP | disclosed |
| JP-4077460-A | — | — | None | — | — | JP | disclosed |
| US-20160263125-A1 | AMINO, AMIDO AND HETEROCYCLIC COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF | NEW YORK UNIVERSITY | 2016-09-15 | — | — | US | disclosed |
| US-20160263125-A1 | AMINO, AMIDO AND HETEROCYCLIC COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF | NEW YORK UNIVERSITY | 2016-09-15 | — | — | US | disclosed |
| US-9364472-B2 | Amino, Amido and heterocyclic compounds as modulators of RAGE activity and uses thereof | NEW YORK UNIVERSITY (US) | 2016-06-14 | — | — | US | disclosed |
| EP-0411817-A2 | Process for preparing N-alkyl-substituted aminophenols | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-02-06 | — | — | EP | disclosed |
| EP-0181505-B1 | IMPROVED METHOD FOR PRODUCING CYCLOALKYL AMINOPHENOL DERIVATIVES | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1990-03-28 | — | — | EP | disclosed |
| WO-1990000046-A1 | HAIR-DYING AGENT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-01-11 | — | — | WO | disclosed |
| EP-0348849-A1 | Hairdying composition | Henkel Kommanditgesellschaft auf Aktien (DE) | 1990-01-03 | — | — | EP | disclosed |
| US-4713488-A | REACTING AMINOPHENOLS AND CYCLOALKANONES IN THE PRESENCE OF A REDUCING AGENT | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1987-12-15 | — | — | US | disclosed |
| JP-S62528-A | POLYAMIDE ESTER AND LIQUID CRYSTAL DISPLAY ELEMENT PREPARED THEREFROM | RICOH CO LTD | 1987-01-06 | — | — | JP | disclosed |
| EP-0181505-A1 | Improved method for producing cycloalkyl aminophenol derivatives | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1986-05-21 | — | — | EP | disclosed |
| EP-0048222-B1 | STABILISATION OF THERMOPLASTICS THAT CONTAIN CHLORINE WITH M-AMINO PHENOLS | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |
| US-4385147-A | Stabilization of chlorine-containing thermoplastics with m-aminophenol derivatives | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |
| EP-0048222-A1 | Stabilisation of thermoplastics that contain chlorine with m-amino phenols | CIBA-GEIGY AG (CH) | 1982-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160263125-A1 | AMINO, AMIDO AND HETEROCYCLIC COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF | AGER, IAPP, GPR119 | CYP3A4 4102/4885TSHR 2272/4885PDK2 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.