Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 3/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618526 | 0.80 | — | — | |
| SCHEMBL2352229 | 0.76 | CALM1 (0.52) | CALM1SORT1LTA4HALDH1A1TP53 | |
| SCHEMBL8086770 | 0.76 | TP53 (0.40) | CALM1SORT1LTA4HTP53KDM4E | |
| SCHEMBL8086710 | 0.73 | CALM1 (0.35) | CALM1LTA4HALDH1A1TP53MAPT | |
| SCHEMBL8087981 | 0.72 | CALM1 (0.42) | CALM1SORT1LTA4HTP53KDM4E | |
| SCHEMBL8090899 | 0.72 | SIGMAR1 (0.37) | CALM1MAOALTA4HALDH1A1 | |
| SCHEMBL8087900 | 0.72 | TP53 (0.40) | CALM1SORT1MAOAMAOBLTA4H | |
| SCHEMBL5953538 | 0.71 | HTR2A (0.42) | CALM1CYP3A4 | |
| SCHEMBL3201380 | 0.69 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4ECYP3A4MAPT | |
| SCHEMBL8079473 | 0.69 | CALM1 (0.35) | CALM1SORT1MAOAMAOBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046346-A | Production of alkali metal cyclopentadienylide and production of dihalobis (η-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0926150-A2 | Production of alkali metal cyclopentadienylide and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide | Honshu Chemical Industry Co. Ltd. (JP) | 1999-06-30 | — | — | EP | disclosed |