Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.67 |
| ▸ | CA1 | P00915 | 6/20 | 0.67 |
| ▸ | CA9 | Q16790 | 4/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylmethanesulfonamide SCHEMBL7371 | 0.80 | CA2 (1.00) | CA2CA1CA9CA5APRSS1 | |
| SCHEMBL7905636 | 0.80 | CA2 (0.58) | CA2CA1CA9CA5APRSS1 | |
| SCHEMBL9798010 | 0.79 | CA2 (0.48) | CA2CA1CA9CA5ACA12 | |
| Phenylmethanesulfonamide SCHEMBL9006012 | 0.78 | CA2 (0.95) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL9400757 | 0.78 | CA2 (0.95) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL4059166 | 0.78 | CA2 (0.95) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL3638470 | 0.78 | CA2 (0.95) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL31442719 | 0.78 | CA2 (0.95) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL4428481 | 0.78 | CA2 (0.95) | CA2CA1CA9CA5APRSS1 | |
| SCHEMBL863300 | 0.76 | CA1 (0.59) | CA2CA1CA9CA5APRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147115-A | SULFONYLUREIDO-4-HALOBENZENE DERIVATIVES; ANTICARCINOGENIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-11-14 | — | — | US | disclosed |
| EP-0467621-B1 | N-phenyl-N'-alkylsulfonylureas, process for their preparation and antitumor compositions containing them | LILLY CO ELI (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5216026-A | Administering to the mammal N-1-butanesulfonamide derivatives and salts | ELI LILLY AND COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0467621-A1 | N-phenyl-N'-alkylsulfonylureas, process for their preparation and antitumor compositions containing them | ELI LILLY AND COMPANY (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0176304-B1 | HERBICIDAL PYRAZOLESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-05 | — | — | EP | disclosed |
| US-4895590-A | Herbicidal pyrazolesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-01-23 | — | — | US | disclosed |
| US-4762550-A | Herbicidal pyrazolesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-08-09 | — | — | US | disclosed |
| US-4705558-A | Herbicidal pyrazolesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-10 | — | — | US | disclosed |
| EP-0176304-A1 | Herbicidal pyrazolesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-02 | — | — | EP | disclosed |