Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090100 | 0.77 | USP2 (0.36) | ALDH1A1PKMHDAC3HDAC1 | |
| SCHEMBL8091485 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1EPHX2POLB | |
| SCHEMBL7435943 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1EPHX2POLB | |
| SCHEMBL7439896 | 0.76 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1EPHX2POLB | |
| SCHEMBL7435936 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1EPHX2POLB | |
| SCHEMBL8095467 | 0.75 | CYP3A4 (0.38) | ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL8095188 | 0.75 | MMP8 (0.39) | TSHR | |
| SCHEMBL8091670 | 0.74 | MMP8 (0.38) | — | |
| SCHEMBL7443545 | 0.73 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1EPHX2POLB | |
| SCHEMBL8090156 | 0.73 | MMP8 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |