Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 3/20 | 0.36 |
| ▸ | F13A1 | P00488 | 2/20 | 0.36 |
| ▸ | TGM1 | P22735 | 2/20 | 0.36 |
| ▸ | TGM6 | O95932 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091489 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1EPHX2POLB | |
| SCHEMBL8098063 | 0.72 | CES2 (0.37) | ALDH1A1POLBPKM | |
| SCHEMBL7435936 | 0.70 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1EPHX2POLB | |
| SCHEMBL8090119 | 0.69 | CAPN1 (0.33) | ALDH1A1EPHX2PKM | |
| SCHEMBL7439896 | 0.68 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1EPHX2POLB | |
| SCHEMBL7435943 | 0.68 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1EPHX2POLB | |
| SCHEMBL7443545 | 0.66 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1EPHX2POLB | |
| SCHEMBL7443535 | 0.64 | KMT2A (0.42) | ALDH1A1KMT2AMEN1EPHX2POLB | |
| SCHEMBL8092142 | 0.63 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1EPHX2POLB | |
| SCHEMBL8091601 | 0.62 | EPHX2 (0.88) | ALDH1A1KMT2AMEN1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |