Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31287265 | 0.83 | TAAR1 (0.39) | CA1CA2CA12CA7CA13 | |
| SCHEMBL22469716 | 0.83 | TAAR1 (0.39) | CA1CA2CA12CA7CA13 | |
| Hydrochloric Acid SCHEMBL1764756 | 0.81 | TAAR1 (0.38) | CA1CA2CA12CA7CA13 | |
| SCHEMBL6963717 | 0.80 | TAAR1 (0.52) | CA1CA2CA12CA7CA13 | |
| SCHEMBL545418 | 0.77 | LOXL2 (0.33) | LOXL2 | |
| SCHEMBL10585053 | 0.74 | TAAR1 (0.36) | CA1CA2CA12CA7CA13 | |
| SCHEMBL622777 | 0.74 | TAAR1 (0.37) | TAAR1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL554229 | 0.74 | SLC6A2 (0.33) | LOXL2 | |
| Hydrochloric Acid SCHEMBL3673293 | 0.74 | LOXL2 (0.32) | LOXL2 | |
| SCHEMBL26321234 | 0.72 | TAAR1 (0.35) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884839-B2 | Inhibitors of 17Beta-hydroxysteroid dehydrogenases type 1 and type 2 | ELEXOPHARM GMBH (DE) | 2018-02-06 | — | — | US | claimed |
| CN-100522925-C | Preparation of 4-methyl-2, 3, 5, 6-tetrafluorobenzyl alcohol | SYNGENTA LTD (GB) | 2009-08-05 | — | — | CN | claimed |
| EP-1339666-B1 | PREPARATION OF 4-METHYL-2,3,5,6-TETRAFLUOROBENZYL ALCOHOL | SYNGENTA LTD (GB) | 2008-04-02 | — | — | EP | claimed |
| CN-1839113-A | Preparation of 4-methyl-2, 3, 5, 6-tetrafluorobenzyl alcohol | SYNGENTA LTD (GB) | 2006-09-27 | — | — | CN | claimed |
| CN-114751807-B | Preparation process of 2,3,5, 6-tetrafluorobenzyl alcohol | 忠同科技(大连)有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-114751807-A | Novel efficient preparation process of 2,3,5, 6-tetrafluorobenzyl alcohol | 忠同科技(大连)有限公司 | 2022-07-15 | — | — | CN | disclosed |
| EP-1893556-B1 | PROCESS FOR PREPARING TETRAFLUOROBENZENE CARBALDEHYDE ALKYL ACETAL | SHOWA DENKO KK (JP) | 2011-11-16 | — | — | EP | disclosed |
| US-7790931-B2 | Process for preparing tetrafluorobenzene carbaldehyde alkyl acetal | SHOWA DENKO K.K. (JP) | 2010-09-07 | — | — | US | disclosed |
| US-20100105954-A1 | PROCESS FOR PREPARING TETRAFLUOROBENZENE CARBALDEHYDE ALKYL ACETAL | SHOWA DENKO K.K. (JP) | 2010-04-29 | — | — | US | disclosed |
| CN-100522925-C | Preparation of 4-methyl-2, 3, 5, 6-tetrafluorobenzyl alcohol | SYNGENTA LTD (GB) | 2009-08-05 | — | — | CN | disclosed |
| EP-1765771-A4 | FORMATION OF TETRA-SUBSTITUTED ENAMIDES AND STEREOSELECTIVE REDUCTION THEREOF | MERCK & CO INC (US) | 2008-04-02 | — | — | EP | disclosed |
| EP-1893556-A2 | PROCESS FOR PREPARING TETRAFLUOROBENZENE CARBALDEHYDE ALKYL ACETAL | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2008-03-05 | — | — | EP | disclosed |
| EP-1765771-A2 | FORMATION OF TETRA-SUBSTITUTED ENAMIDES AND STEREOSELECTIVE REDUCTION THEREOF | Merck & Co., Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006137347-A2 | PROCESS FOR PREPARING TETRAFLUOROBENZENE CARBALDEHYDE ALKYL ACETAL | SHOWA DENKO K.K. (JP) | 2006-12-28 | — | — | WO | disclosed |
| CN-1839113-A | Preparation of 4-methyl-2, 3, 5, 6-tetrafluorobenzyl alcohol | SYNGENTA LTD (GB) | 2006-09-27 | — | — | CN | disclosed |
| WO-2006017045-A2 | FORMATION OF TETRA-SUBSTITUTED ENAMIDES AND STEREOSELECTIVE REDUCTION THEREOF | MERCK & CO., INC. (US) | 2006-02-16 | — | — | WO | disclosed |
| EP-0099622-B1 | PROCESS FOR THE HYDROGENATION OF PERHALOGENATED TEREPHTHALONITRILES TO AMINES, 2,3,5,6-TETRAFLUOROXYLYLENE DIAMINE AND SALTS THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-12-04 | — | — | EP | disclosed |
| EP-0099622-A1 | Process for the hydrogenation of perhalogenated terephthalonitriles to amines, 2,3,5,6-tetrafluoroxylylene diamine and salts thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105954-A1 | PROCESS FOR PREPARING TETRAFLUOROBENZENE CARBALDEHYDE ALKYL ACETAL | ADH1A, ADH1C, ALDH1A1 | CA1 157/4885CA2 1080/4885CA12 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.