SCHEMBL8092012

SCHEMBL8092012

COC(=O)O.NC(CCO)(CCO)CCO

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 2/20 0.33
ARG2 P78540 2/20 0.33
TET2 Q6N021 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
TSHR P16473 1/20 0.31
GGT1 P19440 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
THRB P10828 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL5532861 0.82 FFAR3 (0.39) ARG1ARG2GGT1MEN1ALDH1A1
Bicarbonate SCHEMBL8995795 0.82 ARG2 (0.39) ARG1ARG2GGT1MEN1ALDH1A1
Acetone SCHEMBL7760762 0.79 LMNA (0.35) ARG1ARG2GGT1MEN1ALDH1A1
SCHEMBL2230483 0.77 FDPS (0.42) TSHRMEN1ALDH1A1CYP1A2THRB
Ethylene Glycol SCHEMBL8064439 0.76
SCHEMBL148930 0.76 MEN1 (0.47) ARG1ARG2TSHRMEN1ALDH1A1
SCHEMBL2229652 0.75 ALDH1A1 (0.37) ARG1ARG2TET2EGLN1TSHR
SCHEMBL466172 0.74 CA1 (0.32)
SCHEMBL2473803 0.74 SMPD1 (0.46) TSHRMEN1ALDH1A1KMT2A
SCHEMBL2471652 0.74 SMPD1 (0.46) TSHRMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6130347-A REACTING MONOCHLOROACETIC ESTER WITH HYDROGEN CYANIDE IN BASE PRESENCE; CYANATION BASF AKTIENGESELLSCHAFT (DE) 2000-10-10 US disclosed
US-5516928-A REACTION OF ISOPHORONE AND HYDROGEN CYANIDE USING QUATERNARY AMMONIUM CATALYST BASF AKTIENGESELLSCHAFT (DE) 1996-05-14 US disclosed