Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476355 | 0.92 | PTGS1 (0.48) | PTGS1PTGS2CCR2TDP1MAPT | |
| SCHEMBL8525177 | 0.87 | PTGS1 (0.50) | PTGS1PTGS2CCR2TDP1PTGDR | |
| SCHEMBL8524014 | 0.85 | PTGS1 (0.46) | PTGS1PTGS2CCR2TDP1PTGDR | |
| SCHEMBL8092076 | 0.80 | PTGS1 (0.47) | PTGS1PTGS2CCR2TDP1PTGDR | |
| SCHEMBL7160901 | 0.80 | FFAR1 (0.60) | PTGS1PTGS2CCR2FFAR1PTGDR | |
| SCHEMBL8476353 | 0.77 | TDP1 (0.46) | PTGS1PTGS2CCR2TDP1MAPT | |
| SCHEMBL8524150 | 0.72 | PTGS1 (0.54) | PTGS1PTGS2CCR2PTGDRPTGDR2 | |
| SCHEMBL8481656 | 0.72 | PTGS1 (0.51) | PTGS1PTGS2CCR2FFAR1TDP1 | |
| SCHEMBL8101582 | 0.71 | PTGS1 (0.50) | PTGS1PTGS2CCR2PTGDRPTGDR2 | |
| SCHEMBL2394825 | 0.71 | PTGDR2 (0.53) | PTGS1PTGS2FFAR1TDP1PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848703-B1 | DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLO-OXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 2000-09-27 | — | — | EP | disclosed |