Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525177 | 0.87 | PTGS1 (0.50) | PTGS1PTGS2TDP1CYP19A1CCR2 | |
| SCHEMBL8092078 | 0.85 | PTGS1 (0.48) | PTGS1PTGS2TDP1CYP19A1CCR2 | |
| SCHEMBL8476355 | 0.84 | PTGS1 (0.48) | PTGS1PTGS2TDP1CYP19A1CCR2 | |
| SCHEMBL8092076 | 0.80 | PTGS1 (0.47) | PTGS1PTGS2TDP1CYP19A1CCR2 | |
| SCHEMBL8476353 | 0.79 | TDP1 (0.46) | PTGS1PTGS2TDP1CCR2MAPT | |
| SCHEMBL27627585 | 0.73 | PKM (0.46) | MAPTPKMPOLBMEN1KMT2A | |
| SCHEMBL8524150 | 0.72 | PTGS1 (0.54) | PTGS1PTGS2CCR2MAPTPOLB | |
| SCHEMBL9657574 | 0.71 | PTGS1 (0.60) | PTGS1PTGS2CCR2MAPTSMN1; SMN2 | |
| SCHEMBL8942422 | 0.70 | HPGD (0.45) | PTGS1PTGS2CYP19A1CCR2MAPT | |
| SCHEMBL8101589 | 0.69 | PTGS2 (0.61) | PTGS1PTGS2CYP19A1CCR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004948-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | NYCOMED AUSTRIA GMBH (AT) | 1999-12-21 | — | — | US | disclosed |