Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092259 | 0.87 | USP10 (0.44) | PTGER4GAAMAPTKDM4EMEN1 | |
| SCHEMBL8098272 | 0.87 | UBE2M (0.34) | EPHX2PPARGPOLBHPGD | |
| SCHEMBL8090772 | 0.84 | PTGER4 (0.41) | PTGER4ICAM1SELEGAAMAPT | |
| SCHEMBL8098790 | 0.84 | NPSR1 (0.36) | ICAM1SELEGAAMAPTKDM4E | |
| SCHEMBL8083940 | 0.78 | RHOC (0.36) | PPARGMAPTKDM4EMEN1KMT2A | |
| SCHEMBL8083652 | 0.77 | PPARG (0.36) | PPARGMAPTMEN1KMT2A | |
| SCHEMBL8083716 | 0.76 | AKR1C3 (0.37) | EPHX2PPARGMAPTMAPK1KDM4E | |
| SCHEMBL8098738 | 0.75 | CYP1A2 (0.33) | CYP1A2CYP3A4MAOA | |
| SCHEMBL8083684 | 0.73 | SERPINE1 (0.40) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL8092253 | 0.71 | USP10 (0.48) | PTGER4GAAMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |