SCHEMBL8092296

SCHEMBL8092296

CCCCCC(=C(OC)C(=O)O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.53
CES1 P23141 3/20 0.53
PTGS2 P35354 6/20 0.51
NAAA Q02083 1/20 0.46
ESR1 P03372 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3084634 0.98 CES2 (0.54) CES2CES1PTGS2NAAA
SCHEMBL32074 0.98 CES2 (0.54) CES2CES1PTGS2NAAA
SCHEMBL7096425 0.98 CES2 (0.54) CES2CES1PTGS2NAAA
SCHEMBL5178120 0.95 PTGS2 (0.57) CES2CES1PTGS2NAAAESR1
Stearic Acid SCHEMBL8430839 0.94 CES2 (0.50) CES2CES1PTGS2ESR1
SCHEMBL29717021 0.89 CES2 (0.46) CES2CES1PTGS2NAAA
SCHEMBL7527911 0.89 CES2 (0.46) CES2CES1PTGS2NAAA
SCHEMBL31697573 0.87 CES2 (0.44) CES2CES1PTGS2NAAA
SCHEMBL38663795 0.87 TDP1 (0.50) CES2CES1PTGS2NAAA
Cinnamic Acid SCHEMBL29850611 0.86 TUBB4A (0.50) CES2CES1PTGS2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1059911-A1 FORMULATIONS WITH AN ANTI-VIRAL EFFECT MERCK PATENT GmbH (DE) 2000-12-20 EP disclosed
WO-1999044578-A1 FORMULATIONS WITH AN ANTI-VIRAL EFFECT MERCK PATENT GMBH (DE) 1999-09-10 WO disclosed