Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | PTPRB | P23467 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809243 | 0.86 | DGAT1 (0.40) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL17652959 | 0.84 | HMGCR (0.34) | ALDH1A1DGAT1POLBTSHRPTPRB | |
| SCHEMBL248263 | 0.84 | ALDH1A1 (0.32) | ALDH1A1GAAHSD17B10LMNATDP1 | |
| SCHEMBL29674742 | 0.83 | DGAT1 (0.39) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL9723233 | 0.83 | ALDH1A1 (0.33) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL29693811 | 0.83 | CYP1A2 (0.33) | — | |
| SCHEMBL28132221 | 0.83 | MMP8 (0.40) | ALDH1A1TDP1 | |
| SCHEMBL27795255 | 0.83 | TSHR (0.33) | ALDH1A1TSHRPKMPTPRBKDM4E | |
| SCHEMBL12809727 | 0.81 | TSHR (0.44) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL25302909 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9546261-B2 | Stabilizing of organic material with amino-triazine based mannich-compounds | BOREALIS AG (AT) | 2017-01-17 | — | — | US | disclosed |
| US-20140235766-A1 | Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds | BOREALIS AG (AT) | 2014-08-21 | — | — | US | disclosed |
| US-20080103311-A1 | Retroviral protease inhibitors | PHARMACIA CORPORATION (US) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103311-A1 | Retroviral protease inhibitors | PREP, DNPEP, SERPINB1 | ALDH1A1 2859/4885GAA 126/4885MGAM 713/4885 |
| US-20140235766-A1 | Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds | PCNA, SOD1, UBE2M | ALDH1A1 3108/4885GAA 3145/4885MGAM 894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.