SCHEMBL8092489

SCHEMBL8092489

Nc1cc(NCCCS(=O)(=O)CCO)ccc1S(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.39
ALDH1A1 P00352 2/20 0.38
RAPGEF4 Q8WZA2 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
EGFR P00533 1/20 0.33
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
PRSS1 P07477 6/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
RECQL P46063 1/20 0.32
CASP6 P55212 1/20 0.32
KMT2A Q03164 1/20 0.32
ELAVL1 Q15717 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
F2 P00734 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8079314 0.92 CA2 (0.40) CA2ALDH1A1RAPGEF4CTDSP1EGFR
SCHEMBL8086605 0.90 CTDSP1 (0.44) CA2ALDH1A1RAPGEF4CTDSP1EGFR
SCHEMBL8086551 0.81 CTDSP1 (0.46) CA2ALDH1A1RAPGEF4CTDSP1EGFR
SCHEMBL9243791 0.81 CNR2 (0.46) CA2ALDH1A1RAPGEF4CTDSP1CNR2
SCHEMBL8087846 0.81 ALDH1A1 (0.38) CA2ALDH1A1KDM4ECASP6TDP1
SCHEMBL4824936 0.79 PRSS1 (0.38) CA2ALDH1A1CYP11B1CYP11B2PRSS1
SCHEMBL8092538 0.78 KEAP1 (0.41) CA2ALDH1A1EGFRKDM4EMEN1
SCHEMBL8079295 0.77 DDX3X (0.41) CA2ALDH1A1KDM4EMEN1POLB
SCHEMBL10803735 0.76 CA2 (0.43) CA2ALDH1A1RAPGEF4CTDSP1KDM4E
SCHEMBL8086533 0.75 ALDH1A1 (0.41) CA2ALDH1A1CTDSP1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717084-B1 Water soluble fibre reactive anthraquinone compounds DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-11-22 EP disclosed
EP-0717084-A1 Water soluble fibre reactive anthraquinone compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-06-19 EP disclosed