SCHEMBL8092589

SCHEMBL8092589

O=C(/C=C/C(=O)OC1=NC(CC2=Cc3c(F)cccc3CC2)CN1)OC1=NC(CC2=Cc3c(F)cccc3CC2)CN1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 2/20 0.47
CCKBR P32239 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8092828 0.88 ADRA2A (0.33) ADRA2A
SCHEMBL8096702 0.86 ADRA2A (0.32) ADRA2A
SCHEMBL8091875 0.83 ADRA2A (0.43) ADRA2A
SCHEMBL8085006 0.83 ADRA2A (0.43) ADRA2A
SCHEMBL8092401 0.83 ADRA2A (0.43) ADRA2A
SCHEMBL8097510 0.80 ADRA2A (0.47) ADRA2A
SCHEMBL8090880 0.76 MCHR1 (0.32)
SCHEMBL8093366 0.76 ADRA2A (0.33) ADRA2A
SCHEMBL8097775 0.75 ACHE (0.38) ADRA2A
SCHEMBL27499927 0.75 ADRA2A (0.43) ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127396-A Imidazoline compounds ADIR ET COMPAGNIE (FR) 2000-10-03 US disclosed