Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092401 | 1.00 | ADRA2A (0.43) | ADRA2AHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL8085006 | 1.00 | ADRA2A (0.43) | ADRA2AHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL8097775 | 0.90 | ACHE (0.38) | ADRA2AHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL8093366 | 0.85 | ADRA2A (0.33) | ADRA2A | |
| SCHEMBL8090880 | 0.85 | MCHR1 (0.32) | — | |
| SCHEMBL8097510 | 0.85 | ADRA2A (0.47) | ADRA2A | |
| SCHEMBL8084748 | 0.83 | CYP11B2 (0.39) | ADRA2ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8092828 | 0.83 | ADRA2A (0.33) | ADRA2A | |
| SCHEMBL8092589 | 0.83 | ADRA2A (0.47) | ADRA2A | |
| SCHEMBL8096702 | 0.81 | ADRA2A (0.32) | ADRA2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |