Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092828 | 0.88 | ADRA2A (0.33) | ADRA2A | |
| SCHEMBL8092589 | 0.86 | ADRA2A (0.47) | ADRA2A | |
| SCHEMBL8091875 | 0.81 | ADRA2A (0.43) | ADRA2ACYP19A1 | |
| SCHEMBL8085006 | 0.81 | ADRA2A (0.43) | ADRA2ACYP19A1 | |
| SCHEMBL8092401 | 0.81 | ADRA2A (0.43) | ADRA2ACYP19A1 | |
| SCHEMBL8084748 | 0.78 | CYP11B2 (0.39) | ADRA2AMTNR1AMTNR1BCYP19A1 | |
| Fumaric Acid SCHEMBL8096698 | 0.77 | ADRA2A (0.34) | ADRA2APARP1ALDH1A1KDM4EMAPT | |
| Fumaric Acid SCHEMBL8096703 | 0.77 | ADRA2A (0.34) | ADRA2APARP1ALDH1A1KDM4EMAPT | |
| SCHEMBL8097510 | 0.76 | ADRA2A (0.47) | ADRA2A | |
| SCHEMBL8093366 | 0.76 | ADRA2A (0.33) | ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |