Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11459008 | 0.88 | CFTR (0.39) | POLBALDH1A1MAPTNPSR1CYP1A2 | |
| SCHEMBL8092437 | 0.84 | ADRA2A (0.43) | POLBMAPTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL8092415 | 0.84 | BRD4 (0.39) | ALDH1A1L3MBTL1MAPTCYP1A2CYP2C9 | |
| SCHEMBL6951250 | 0.82 | PSEN1 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL8096734 | 0.81 | PPARG (0.42) | CYP11B2ALDH1A1GAAMAPTCYP1A2 | |
| SCHEMBL8091366 | 0.78 | NOTUM (0.43) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL27500226 | 0.76 | HTR2A (0.36) | — | |
| SCHEMBL8099968 | 0.76 | MCHR1 (0.42) | ALDH1A1L3MBTL1MAPTCYP1A2CYP2C9 | |
| SCHEMBL7071372 | 0.74 | PPARG (0.41) | POLBALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL19985008 | 0.73 | NQO2 (0.43) | CYP11B1CYP11B2POLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183907-C | Imidazoline compound, preparing process thereof and pharmaceutical composition contg. same | SERVIER LAB (FR) | 2005-01-12 | — | — | CN | disclosed |
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |