Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092415 | 0.86 | BRD4 (0.39) | LMNAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8092602 | 0.84 | TRPM2 (0.40) | MAPTNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8096734 | 0.83 | PPARG (0.42) | MAPTMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL6952817 | 0.81 | ADRA2A (0.48) | ADRA2AMEN1KMT2ATSHRHTT | |
| SCHEMBL21474553 | 0.81 | TSHR (0.43) | ADRA2AMAPK14LMNAMAPTMEN1 | |
| SCHEMBL8091366 | 0.80 | NOTUM (0.43) | ADRA2ALMNATSHRHPGD | |
| SCHEMBL8099968 | 0.78 | MCHR1 (0.42) | LMNAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7071372 | 0.76 | PPARG (0.41) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8097781 | 0.75 | ADRA2A (0.43) | ADRA2AMEN1KMT2ATSHRNLRP3 | |
| SCHEMBL7309377 | 0.73 | PLAU (0.47) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183907-C | Imidazoline compound, preparing process thereof and pharmaceutical composition contg. same | SERVIER LAB (FR) | 2005-01-12 | — | — | CN | disclosed |
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |