Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099968 | 0.89 | MCHR1 (0.42) | BRD4NLRP3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8092437 | 0.86 | ADRA2A (0.43) | BRD4NLRP3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8096734 | 0.85 | PPARG (0.42) | BRD4CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8092602 | 0.84 | TRPM2 (0.40) | BRD4CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6958447 | 0.84 | SRC (0.40) | SMN1; SMN2ALDH1A1MAPTMCHR1 | |
| SCHEMBL8091366 | 0.82 | NOTUM (0.43) | SMN1; SMN2ALDH1A1HSD17B10LMNAL3MBTL1 | |
| SCHEMBL7071372 | 0.79 | PPARG (0.41) | BRD4NLRP3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27500544 | 0.75 | HTR1A (0.34) | MCHR1 | |
| SCHEMBL7309377 | 0.75 | PLAU (0.47) | SMN1; SMN2ALDH1A1LMNAMAPTMCHR1 | |
| SCHEMBL7308827 | 0.74 | LMNA (0.47) | SMN1; SMN2LMNAMAPTMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183907-C | Imidazoline compound, preparing process thereof and pharmaceutical composition contg. same | SERVIER LAB (FR) | 2005-01-12 | — | — | CN | disclosed |
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |