Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.44 |
| ▸ | HTR3A | P46098 | 4/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088026 | 0.84 | HTR2C (0.40) | HTR2BHTR3AHTR4HTR2CHTR7 | |
| SCHEMBL8091569 | 0.83 | CYP3A4 (0.49) | ATMHTR2ADRD2HRH1GRIN1 | |
| SCHEMBL8102227 | 0.80 | GRIN1 (0.42) | HTR2BHTR3AHTR4HTR2CHTR7 | |
| SCHEMBL8102177 | 0.79 | GPR6 (0.47) | ATMHTR1A | |
| SCHEMBL8095854 | 0.78 | KDM4E (0.46) | HTR2BHTR3AHTR4HTR2CHTR7 | |
| SCHEMBL8101941 | 0.78 | KDM4E (0.45) | HTR2BHTR3AHTR4HTR2CHTR7 | |
| SCHEMBL8094653 | 0.77 | PDE2A (0.47) | HTR2BATMCHRM4ACHE | |
| SCHEMBL8103772 | 0.74 | DPP4 (0.43) | ATMHTR1AGRIN1GRIN2BACHE | |
| SCHEMBL13945390 | 0.74 | AR (0.39) | HTR2BHTR3AHTR4HTR2CHTR7 | |
| SCHEMBL8102582 | 0.73 | DPP4 (0.49) | HTR2BHTR4HTR7HTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000085-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-12-31 | — | — | WO | disclosed |