Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13945322 | 0.83 | SCN9A (0.46) | KDM4EALDH1A1TDP1TRPV6CHRNB2 | |
| SCHEMBL8095854 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL8102177 | 0.78 | GPR6 (0.47) | KDM4EALDH1A1KMT2AMEN1ATM | |
| SCHEMBL8092993 | 0.78 | HTR2B (0.44) | ATMHTR1AHTR2CHTR7HTR2B | |
| SCHEMBL21063255 | 0.77 | ADORA2A (0.45) | KDM4EALDH1A1TDP1CHRNB2CHRNA4 | |
| SCHEMBL8102227 | 0.75 | GRIN1 (0.42) | KDM4EKMT2AMEN1NPC1MAPT | |
| SCHEMBL8100325 | 0.71 | JAK2 (0.39) | ALDH1A1NPC1HTR1AHTR2CHTR7 | |
| SCHEMBL5526683 | 0.71 | SCN1A (0.50) | KDM4ESMN1; SMN2 | |
| SCHEMBL8430036 | 0.71 | CHRNB2 (0.64) | KDM4EALDH1A1TDP1TRPV6CHRNB2 | |
| SCHEMBL803669 | 0.69 | CHRNB2 (0.60) | KDM4EALDH1A1TDP1TRPV6CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000085-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-12-31 | — | — | WO | disclosed |